2019年1月3日星期四

Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products

Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products

BI Morinaka, AL Vagstad, MJ Helf… - Angewandte Chemie …, 2014 - Wiley Online Library
PoyD is a radical S‐adenosyl methionine epimerase that introduces multiple d‐configured
amino acids at alternating positions into the highly complex marine peptides
polytheonamide A and B. This novel post‐translational modification contributes to the ability …


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