Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA–B27 allotypes

Revisiting the arthritogenic peptide theory: quantitative not qualitative changes in the peptide repertoire of HLA–B27 allotypes

RB Schittenhelm, TCCLK Sian… - Arthritis & …, 2015 - Wiley Online Library

Objective The association of HLA–B27 with spondyloarthropathy is one of the strongest
documented for any autoimmune disease. A common hypothesis for this association is the
arthritogenic peptide concept. This dictates that differences in the peptide binding …

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