Sequence-selective targeting of duplex DNA by peptide nucleic acids.

Sequence-selective targeting of duplex DNA by peptide nucleic acids.

PE Nielsen - Current opinion in molecular therapeutics, 2010 - europepmc.org

Sequence-selective gene targeting constitutes an attractive drug-discovery approach for
genetic therapy, with the aim of reducing or enhancing the activity of specific genes at the
transcriptional level, or as part of a methodology for targeted gene repair. The …

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