2019年1月1日星期二

Topical delivery of siRNA into skin using SPACE-peptide carriers

Topical delivery of siRNA into skin using SPACE-peptide carriers

M Chen, M Zakrewsky, V Gupta, AC Anselmo… - Journal of Controlled …, 2014 - Elsevier
Short-interfering RNAs (siRNAs) offer a potential tool for the treatment of skin disorders.
However, applications of siRNA for dermatological conditions are limited by their poor
permeation across the stratum corneum of the skin and low penetration into the skin's viable …


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