2018年5月4日星期五

Predicted MHC peptide binding promiscuity explains MHC class I 'hotspots' of antigen presentation defined by mass spectrometry eluted ligand data

Predicted MHC peptide binding promiscuity explains MHC class I 'hotspots' of antigen presentation defined by mass spectrometry eluted ligand data

EC Jappe, J Kringelum, T Trolle, M Nielsen - Immunology, 2018 - Wiley Online Library
Peptides that bind to and are presented by MHC class I and class II molecules collectively
make up the immunopeptidome. In the context of vaccine development, an understanding of
the immunopeptidome is essential, and much effort has been dedicated to its accurate and …


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