Synthesis and pharmaceutical characterization of site specific mycophenolic acid-modified Xenopus glucagon-like peptide-1 analogs
J Han, J Fu, L Sun, Y Han, Q Mao, F Liao, X Zheng… - …, 2018 - pubs.rsc.org
To develop novel long-acting antidiabetic agents, mycophenolic acid (MPA) was used to
modify Xenopus glucagon-like peptide-1 analog (GLP-1)(1) at three Lys residues through a
γ-glutamyl linker. Similarly, 6-aminocaproic acid and 12-aminolauric acid with different …
modify Xenopus glucagon-like peptide-1 analog (GLP-1)(1) at three Lys residues through a
γ-glutamyl linker. Similarly, 6-aminocaproic acid and 12-aminolauric acid with different …
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