2018年7月30日星期一

Expression of familial A lzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue …

Expression of familial A lzheimer disease presenilin 1 gene attenuates vesicle traffic and reduces peptide secretion in cultured astrocytes devoid of pathologic tissue …

M Stenovec, S Trkov, E Lasič, S Terzieva, M Kreft… - Glia, 2016 - Wiley Online Library
In the brain, astrocytes provide metabolic and trophic support to neurones. Failure in
executing astroglial homeostatic functions may contribute to the initiation and propagation of
diseases, including Alzheimer disease (AD), characterized by a progressive loss of …


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