2018年7月30日星期一

Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer

Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer

J Huang, X Zeng, N Sigal, PJ Lund… - Proceedings of the …, 2016 - National Acad Sciences
Here we report a peptide-MHC (pMHC) dodecamer as a “next generation” technology that is
a significantly more sensitive and versatile alternative to pMHC tetramers for the detection,
isolation, and phenotypic analysis of antigen-specific T cells. In particular, dodecamers are …


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