Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy

Targeting dendritic cells in lymph node with an antigen peptide-based nanovaccine for cancer immunotherapy

Y Qian, H Jin, S Qiao, Y Dai, C Huang, L Lu, Q Luo… - Biomaterials, 2016 - Elsevier

The design of peptide-based subunit vaccine formulations for the direct delivery of tumor
antigen peptides (Aps) to dendritic cells (DCs) localized within draining lymph nodes (DLNs)
is challenging. Mature DCs (mDCs) are abundantly distributed within DLNs but have …

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