[HTML] Familial Alzheimer's disease mutations in presenilin generate amyloidogenic Aβ peptide seeds

[HTML] Familial Alzheimer's disease mutations in presenilin generate amyloidogenic Aβ peptide seeds

S Veugelen, T Saito, TC Saido, L Chávez-Gutiérrez… - Neuron, 2016 - Elsevier

Recently it was proposed that the familial Alzheimer's disease (FAD) causing presenilin
(PSEN) mutations PSEN1-L435F and PSEN1-C410Y do not support the generation of Aβ-
peptides from the amyloid precursor protein (APP). This challenges the amyloid hypothesis …

For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:

*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.

*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.

*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.

*Peptide Salt: TFA, Desalt, Acetate, HCl.

*Peptide Purity: From crude to ＞99.5%.

*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.

*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.

Quick Links:

Peptide Price
Peptide Modification
Peptide Library
Quote Request
Contact Us

Contact Information:

Eva He
eva@pepmic.com

Pepmic Co., Ltd
www.pepmic.com