2018年7月30日星期一

Nascent peptide assists the ribosome in recognizing chemically distinct small molecules

Nascent peptide assists the ribosome in recognizing chemically distinct small molecules

P GuptaB Liu, D Klepacki, V GuptaK Schulten… - Nature chemical …, 2016 - nature.com
Regulation of gene expression in response to the changing environment is critical for cell
survival. For instance, binding of macrolide antibiotics to the ribosome promotes translation
arrest at the leader open reading frames ermCL and ermBL, which is necessary for inducing …


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