Oxadiazole grafts in peptide macrocycles
JR Frost, CCG Scully, AK Yudin - Nature Chemistry, 2016 - nature.com
Synthetic methods that provide control over macrocycle conformation and, at the same time,
mitigate the polarity of peptide bonds represent valuable tools for the discovery of new
bioactive molecules. Here, we report a macrocyclization reaction between a linear peptide …
mitigate the polarity of peptide bonds represent valuable tools for the discovery of new
bioactive molecules. Here, we report a macrocyclization reaction between a linear peptide …
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