Structural modeling of HLA-B* 1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced …

Structural modeling of HLA-B* 1502/peptide/carbamazepine/T-cell receptor complex architecture: implication for the molecular mechanism of carbamazepine-induced …

P Zhou, S Zhang, Y Wang, C Yang… - Journal of Biomolecular …, 2016 - Taylor & Francis

Drug-induced adverse reactions are a significant problem in healthcare worldwide and are
estimated to cost billions of dollars annually in the United States. A portion of such reactions
is observed to strongly associate with certain human leukocyte antigen (HLA) alleles; one of …

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