A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical …
G Thom, MM Tian, JP Hatcher… - Journal of Cerebral …, 2018 - journals.sagepub.com
Delivery of biologic drugs across the blood–brain barrier is becoming a reality. However, the
solutions often involve the assembly of complex multi-specific antibody molecules. Here we
utilize a simple 12 amino-acid peptide originating from the melanotransferrin (MTf) protein …
solutions often involve the assembly of complex multi-specific antibody molecules. Here we
utilize a simple 12 amino-acid peptide originating from the melanotransferrin (MTf) protein …
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