An Orthogonal D2O‐Based Induction System that Provides Insights into d‐Amino Acid Pattern Formation by Radical S‐Adenosylmethionine Peptide Epimerases

An Orthogonal D₂O‐Based Induction System that Provides Insights into d‐Amino Acid Pattern Formation by Radical S‐Adenosylmethionine Peptide Epimerases

BI Morinaka, M Verest, MF Freeman… - Angewandte …, 2017 - Wiley Online Library

Radical S‐adenosyl methionine peptide epimerases (RSPEs) are an enzyme family that
accomplishes regiospecific and irreversible introduction of multiple d‐configured residues
into ribosomally encoded peptides. Collectively, RSPEs can generate diverse epimerization …

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