Caspase-13 Antibody

Product	Caspase-13 Antibody
Cat#	100-2-44A
Unit/Weight	100 μg
Unit Price	$311.00
Species Reactivity	H, M, R
Tested Application(s)	E, WB, IHC
Brief Description	Evolutionarily Related ICE
Specific Description	Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 b Converting Enzyme) and caspase-13?(1). Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines (1).
Storage	Caspase-13 antibody can be stored at 4°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.