2018年12月19日星期三

CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading

CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading

K Miura, T Nojiri, Y Akitake, K Ando, S Fukuhara… - Biochemical …, 2017 - biochemj.org
Atrial natriuretic peptide (ANP) is a cardiac hormone released by the atrium in response to
stretching forces. Via its receptor, guanylyl cyclase-A (GC-A), ANP maintains cardiovascular
homeostasis by exerting diuretic, natriuretic, and hypotensive effects mediated, in part, by …


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