Comprehensive computational design of ordered peptide macrocycles
P Hosseinzadeh, G Bhardwaj, VK Mulligan… - …, 2017 - science.sciencemag.org
Mixed-chirality peptide macrocycles such as cyclosporine are among the most potent
therapeutics identified to date, but there is currently no way to systematically search the
structural space spanned by such compounds. Natural proteins do not provide a useful …
therapeutics identified to date, but there is currently no way to systematically search the
structural space spanned by such compounds. Natural proteins do not provide a useful …
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