[HTML] Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate

[HTML] Assaying kinase activity of the TPL-2/NF-κB1 p105/ABIN-2 complex using an optimal peptide substrate

S Kümper, T Gantke, CS Chen, Y Soneji… - Biochemical …, 2018 - biochemj.org

The MKK1/2 kinase tumour progression locus 2 (TPL-2) is critical for the production of
tumour necrosis factor alpha (TNFα) in innate immune responses and a potential anti-
inflammatory drug target. Several earlier pharmaceutical company screens with the isolated …

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