Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally sensitive transmembrane peptide

Selective delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally sensitive transmembrane peptide

YK Reshetnyak, OA Andreev, U Lehnert… - US Patent …, 2017 - Google Patents

A polypeptide with a predominantly hydrophobic sequence long enough to span a
membrane lipid bilayer as a transmembrane helix (TM) and comprising one or more
dissociable groups inserts across a membrane spontaneously in a pH-dependant fashion …

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