Structural mechanism underpinning cross-reactivity of a CD8+ T-cell clone that recognizes a peptide derived from human telomerase reverse transcriptase
DK Cole, HA van den Berg, A Lloyd… - Journal of Biological …, 2017 - ASBMB
T-cell cross-reactivity is essential for effective immune surveillance but has also been
implicated as a pathway to autoimmunity. Previous studies have demonstrated that T-cell
receptors (TCRs) that focus on a minimal motif within the peptide are able to facilitate a high …
implicated as a pathway to autoimmunity. Previous studies have demonstrated that T-cell
receptors (TCRs) that focus on a minimal motif within the peptide are able to facilitate a high …
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