Biophysical and Biological Evaluation of Optimized Stapled Peptide Inhibitors of the Linear Ubiquitin Chain Assembly Complex (LUBAC)
F Aguilar-Alonso, AL Whiting, YJ Kim… - Bioorganic & medicinal …, 2017 - Elsevier
Abstract Linear ubiquitylation, in which ubiquitin units are covalently linked through N-and C-
terminal amino acids, is a unique cellular signaling mechanism. This process is controlled
by a single E3 ubiquitin ligase, the linear ubiquitin chain assembly complex (LUBAC), which
terminal amino acids, is a unique cellular signaling mechanism. This process is controlled
by a single E3 ubiquitin ligase, the linear ubiquitin chain assembly complex (LUBAC), which
For custom peptides, please visit www.pepmic.com. Our peptide services including but not limited to:
*Peptide Synthesis: From short peptides to long peptides, linear peptides to cyclic peptides.
*Peptide Modifications: Peptide-protein conjugation, D-amino acid peptides, isotope peptides, fluorescent peptides, multiple antigen peptides, multiple disulfide bridge peptides, phosphopeptides etc.
*Catalog Peptides: ACE Inhibitors, Amyloids & Related Peptides, Antimicrobial Peptides, Apelin Peptides, Myelin Oligodendrocyte Glycoprotein (MOG) Peptides, TAT Proteins etc.
*Peptide Salt: TFA, Desalt, Acetate, HCl.
*Peptide Purity: From crude to ＞99.5%.
*Production Capacity: From mg to kg, with a capacity of synthesizing 15,000 peptides/month.
*Peptide Library Synthesis: Alanine Scan, Overlapping, Positional Scan, T-cell Truncated, Scrambled ect.
Quick Links:
Contact Information:
Eva He
eva@pepmic.com
Pepmic Co., Ltdeva@pepmic.com
www.pepmic.com
没有评论:
发表评论