2017年12月28日星期四

PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo

PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo

G Aldrian, A Vaissière, K Konate, Q Seisel… - Journal of Controlled …, 2017 - Elsevier
Abstract Small interfering RNAs (siRNAs) present a strong therapeutic potential because of
their ability to inhibit the expression of any desired protein. Recently, we developed the retro-
inverso amphipathic RICK peptide as novel non-covalent siRNA carrier. This peptide is able


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1 条评论:

  1. It has long been a dream in medicine and pharmacy to use peptides and proteins as drugs. Peptide PEGylation

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