Antimicrobials inspired by nonribosomal peptide synthetase gene clusters
X Vila-Farres, J Chu, D Inoyama… - Journal of the …, 2017 - ACS Publications
Bacterial culture broth extracts have been the starting point for the development of numerous
therapeutics. However, only a small fraction of bacterial biosynthetic diversity is accessible
using this strategy. Here, we apply a discovery approach that bypasses the culturing step
therapeutics. However, only a small fraction of bacterial biosynthetic diversity is accessible
using this strategy. Here, we apply a discovery approach that bypasses the culturing step
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