Urea-containing peptide boronic acids as potent proteasome inhibitors
LQ Han, X Yuan, XY Wu, RD Li, B Xu, Q Cheng… - European journal of …, 2017 - Elsevier
Abstract A novel class of urea-containing peptide boronic acids as proteasome inhibitors
was designed by introducing a urea scaffold to replace an amido bond. Compounds were
synthesized and their antitumor activities were evaluated. After two rounds of optimizations,
was designed by introducing a urea scaffold to replace an amido bond. Compounds were
synthesized and their antitumor activities were evaluated. After two rounds of optimizations,
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