Long-term Functioning of Allogeneic Islets in Subcutaneous Tissue Pretreated with a Novel Cyclic Peptide without Immunosuppressive Medication.

Long-term Functioning of Allogeneic Islets in Subcutaneous Tissue Pretreated with a Novel Cyclic Peptide without Immunosuppressive Medication.

R Kuwabara, M Hamaguchi, T Fukuda, H Sakai… - …, 2017 - europepmc.org

Abstract There exists a need for a minimally invasive method of islet transplantation without
immunosuppressive drugs for the treatment of type 1 diabetes. In diabetic ACI rats, an
agarose rod containing the cyclic oligopeptide SEK-1005 (agarose-SEK rod) was implanted

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