Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance

Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance

W Wu, F Shi, D Liu, RP Ceddia, R Gaffin, W Wei… - Sci. Signal …, 2017 - stke.sciencemag.org

In addition to controlling blood pressure, cardiac natriuretic peptides (NPs) can stimulate
lipolysis in adipocytes and promote the “browning” of white adipose tissue. NPs may also
increase the oxidative capacity of skeletal muscle. To unravel the contribution of NP-

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