Novel DOCK2-selective inhibitory peptide that suppresses B-cell line migration
K Sakamoto, Y Adachi, Y Komoike, Y Kamada… - Biochemical and …, 2017 - Elsevier
Abstract Dedicator of cytokinesis 2 (DOCK2) is a key molecule for lymphocyte activation and
migration. DOCK2 interacts with Ras-related C3 botulinus toxin substrate 1 (Rac1, GTPase)
and mediates the GDP-GTP exchange reaction, indicating that inhibitors against protein-
migration. DOCK2 interacts with Ras-related C3 botulinus toxin substrate 1 (Rac1, GTPase)
and mediates the GDP-GTP exchange reaction, indicating that inhibitors against protein-
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