2018年2月4日星期日

Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

U Gether, TE Johansen, RM Snider, JA Lowe III… - Nature, 1993 - nature.com
Abstract NON-PEPTIDE ligands for peptide receptors have been discovered in several
systems through file screening programs 1–6, but the mechanism of action for these
candidate drugs is obscure as they do not chemically resemble the native peptides. The


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