A Tumor Targeted Chimeric Peptide for Synergistic Endosomal Escape and Therapy by Dual‐Stage Light Manipulation
K Han, Q Lei, HZ Jia, SB Wang, WN Yin… - Advanced Functional …, 2015 - Wiley Online Library
Abstract In this study, a pH sensitive chimeric peptide is developed to codeliver a
photosensitizer, protoporphyrin IX (PpIX), and plasmid DNA simultaneously. In the presence
of matrix metalloproteinase-2 (MMP-2), the chimeric peptide undergoes the process of
photosensitizer, protoporphyrin IX (PpIX), and plasmid DNA simultaneously. In the presence
of matrix metalloproteinase-2 (MMP-2), the chimeric peptide undergoes the process of
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