2018年2月25日星期日

Applying the Retro‐Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood–Brain Barrier

Applying the Retro‐Enantio Approach To Obtain a Peptide Capable of Overcoming the Blood–Brain Barrier

R Prades, B Oller‐Salvia… - Angewandte Chemie …, 2015 - Wiley Online Library
Abstract The blood–brain barrier (BBB) is a formidable physical and enzymatic barrier that
tightly controls the passage of molecules from the blood to the brain. In fact, less than 2% of
all potential neurotherapeutics are able to cross it. Here, by applying the retro-enantio


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