2018年2月25日星期日

Enhanced blood–brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system

Enhanced blood–brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system

H Yao, K Wang, Y Wang, S Wang, J Li, J Lou, L Ye… - Biomaterials, 2015 - Elsevier
Abstract Successful glioma gene therapy lays on two important factors, the therapeutic
genes and efficient delivery vehicles to cross the blood–brain barrier (BBB) and reach
gliomas. In this work, a new gene vector was constructed based on dendrigraft poly-l-lysines


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