2018年2月27日星期二

[HTML] Elevated plasma B-type natriuretic peptide concentrations directly inhibit circulating neprilysin activity in heart failure

[HTML] Elevated plasma B-type natriuretic peptide concentrations directly inhibit circulating neprilysin activity in heart failure

N Vodovar, MF Séronde, S Laribi, E Gayat, J Lassus… - JACC: Heart Failure, 2015 - Elsevier
Abstract Objectives This study sought to hypothesize that elevated B-type natriuretic peptide 
(BNP) could act as an endogenous neprilysin inhibitor. Background A hallmark of acute
decompensated heart failure (ADHF) is the overproduction of natriuretic peptides (NPs) by


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