2018年2月26日星期一

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

T Mizui, Y Ishikawa, H Kumanogoh… - Proceedings of the …, 2015 - National Acad Sciences
Abstract Most growth factors are initially synthesized as precursor proteins and subsequently
processed into their mature form by proteolytic cleavage, resulting in simultaneous removal
of a pro-peptide. However, compared with that of mature form, the biological role of the pro-


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