2018年2月25日星期日

[HTML] An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions

[HTML] An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions

DW Leung, D BorekP Luthra, JM Binning… - Cell reports, 2015 - Elsevier
Summary During viral RNA synthesis, Ebola virus (EBOV) nucleoprotein (NP) alternates
between an RNA-template-bound form and a template-free form to provide the viral
polymerase access to the RNA template. In addition, newly synthesized NP must be


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