Enhancing glioblastoma-specific penetration by functionalization of nanoparticles with an iron-mimic peptide targeting transferrin/transferrin receptor complex

Enhancing glioblastoma-specific penetration by functionalization of nanoparticles with an iron-mimic peptide targeting transferrin/transferrin receptor complex

T Kang, M Jiang, D Jiang, X Feng, J Yao… - Molecular …, 2015 - ACS Publications

Treatment of glioblastoma (GBM) remains to be the most formidable challenge because of
the hindrance of the blood–brain barrier (BBB) along with the poor drug penetration into the
glioma parenchyma. Nanoparticulate drug delivery systems (DDS) utilizing transferrin (Tf) as

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