2018年2月28日星期三

Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens

Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens

B Bufe, T Schumann, R Kappl, I Bogeski… - Journal of Biological …, 2015 - ASBMB
Results: We report the identification of bacterial signal peptides as potent activators of
mammalian FPRs and innate immune responses and define critical features underlying FPR
peptide recognition. Conclusion: These findings identify a molecular signature for FPR


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