Lead discovery and optimization strategies for peptide macrocycles
A Bhat, LR Roberts, JJ Dwyer - European journal of medicinal chemistry, 2015 - Elsevier
Abstract Peptide macrocycles represent a chemical space where the best of biological tools
can synergize with the best of chemical approaches in the quest for leads against
undruggable targets. Peptide macrocycles offer some key advantages in both lead discovery
can synergize with the best of chemical approaches in the quest for leads against
undruggable targets. Peptide macrocycles offer some key advantages in both lead discovery
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