Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
D Ganguly, G Chamilos, R Lande… - Journal of …, 2009 - jem.rupress.org
Dendritic cell (DC) responses to extracellular self-DNA and self-RNA are prevented by the
endosomal seclusion of nucleic acid–recognizing Toll-like receptors (TLRs). In psoriasis,
however, plasmacytoid DCs (pDCs) sense self-DNA that is transported to endosomal TLR9
endosomal seclusion of nucleic acid–recognizing Toll-like receptors (TLRs). In psoriasis,
however, plasmacytoid DCs (pDCs) sense self-DNA that is transported to endosomal TLR9
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