Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers
AP Laudano, RF Doolittle - Proceedings of the National …, 1978 - National Acad Sciences
Abstract A series of small peptides corresponding to the amino termini of the fibrin α-and β-
chains has been synthesized. The peptides glycyl-L-prolyl-L-arginyl-L-proline and glycyl-L-
prolyl-L-arginylsarcosine are potent inhibitors of fibrin polymerization. Moreover, these
chains has been synthesized. The peptides glycyl-L-prolyl-L-arginyl-L-proline and glycyl-L-
prolyl-L-arginylsarcosine are potent inhibitors of fibrin polymerization. Moreover, these
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