2018年2月4日星期日

Trimethylsilyl iodide as a peptide deblocking agent

Trimethylsilyl iodide as a peptide deblocking agent

RS Lott, VS Chauhan, CH Stammer - Journal of the Chemical Society …, 1979 - pubs.rsc.org
EVEN though an earlier report by Rabinowitzl on alkyl phosphonate cleavage by trimethylsilyl
chloride excited little interest, the development of the analogous trimethyl- silyl iodide (TMSI)
as a non-hydrolytic reagent for the cleavage of alkyl esters,% ethers,z acetals,2~


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