2018年2月9日星期五

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

K Haslinger, M Peschke, C Brieke, E Maximowitsch… - Nature, 2015 - nature.com
Abstract Non-ribosomal peptide synthetase (NRPS) mega-enzyme complexes are modular
assembly lines that are involved in the biosynthesis of numerous peptide metabolites
independently of the ribosome 1. The multiple interactions between catalytic domains within


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