2018年5月1日星期二

pH-Sensitive Coiled-Coil Peptide-Cross-Linked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells

pH-Sensitive Coiled-Coil Peptide-Cross-Linked Hyaluronic Acid Nanogels: Synthesis and Targeted Intracellular Protein Delivery to CD44 Positive Cancer Cells

L Ding, Y Jiang, J Zhang, HA KlokZ Zhong - Biomacromolecules, 2018 - ACS Publications
The clinical translation of protein drugs that act intracellularly is limited by the absence of
safe and efficient intracellular protein delivery vehicles. Here, pH-sensitive coiled-coil
peptide-cross-linked hyaluronic acid nanogels (HA-cNGs) were designed and investigated …


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