2018年7月20日星期五

Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo

Discovery and characterization of a peptide that enhances endosomal escape of delivered proteins in vitro and in vivo

M Li, Y Tao, Y Shu, JR LaRochelle… - Journal of the …, 2015 - ACS Publications
The inefficient delivery of proteins into mammalian cells remains a major barrier to realizing
the therapeutic potential of many proteins. We and others have previously shown that
superpositively charged proteins are efficiently endocytosed and can bring associated …


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