2018年7月22日星期日

Peptide immunoaffinity enrichment and targeted mass spectrometry enables multiplex, quantitative pharmacodynamic studies of phospho-signaling

Peptide immunoaffinity enrichment and targeted mass spectrometry enables multiplex, quantitative pharmacodynamic studies of phospho-signaling

JR Whiteaker, L Zhao, P Yan, RG Ivey… - Molecular & cellular …, 2015 - ASBMB
In most cell signaling experiments, analytes are measured one Western blot lane at a time in
a semi-quantitative and often poorly specific manner, limiting our understanding of network
biology and hindering the translation of novel therapeutics and diagnostics. We demonstrate …


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