Robust anti‐obesity and metabolic effects of a dual GLP‐1/glucagon receptor peptide agonist in rodents and non‐human primates
SJ Henderson, A Konkar, DC Hornigold… - Diabetes, Obesity …, 2016 - Wiley Online Library
Aims To characterize the pharmacology of MEDI0382, a peptide dual agonist of glucagon‐
like peptide‐1 (GLP‐1) and glucagon receptors. Materials and methods MEDI0382 was
evaluated in vitro for its ability to stimulate cAMP accumulation in cell lines expressing …
like peptide‐1 (GLP‐1) and glucagon receptors. Materials and methods MEDI0382 was
evaluated in vitro for its ability to stimulate cAMP accumulation in cell lines expressing …
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