The Alzheimer's disease peptide β‐amyloid promotes thrombin generation through activation of coagulation factor XII
D Zamolodchikov, T Renné… - Journal of Thrombosis …, 2016 - Wiley Online Library
Essentials How the Alzheimer's disease (AD) peptide β‐amyloid (Aβ) disrupts neuronal
function in the disease is unclear. Factor (F) XII initiates blood clotting via FXI, and
thrombosis has been implicated in AD. Aβ triggers FXII‐dependent FXI and thrombin …
function in the disease is unclear. Factor (F) XII initiates blood clotting via FXI, and
thrombosis has been implicated in AD. Aβ triggers FXII‐dependent FXI and thrombin …
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