2018年12月23日星期日

A Novel Soluble Peptide with pH-Responsive Membrane Insertion

A Novel Soluble Peptide with pH-Responsive Membrane Insertion

VP Nguyen, DS Alves, HL Scott, FL Davis, FN Barrera - Biophysical Journal, 2016 - cell.com
Several diseases, such as cancer, are characterized by acidification of the extracellular
environment. Acidosis can be employed as a target to specifically direct therapies to the
diseased tissue. We have used first principles to design an acidity-triggered rational …


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