Hexokinase II–derived cell-penetrating peptide targets mitochondria and triggers apoptosis in cancer cells
AD Woldetsadik, MC Vogel, WM Rabeh… - The FASEB Journal, 2017 - fasebj.org
Overexpression of mitochondria-bound hexokinase II (HKII) in cancer cells plays an
important role in their metabolic reprogramming and protects them against apoptosis,
thereby facilitating their growth and proliferation. Here, we show that covalently coupling a …
important role in their metabolic reprogramming and protects them against apoptosis,
thereby facilitating their growth and proliferation. Here, we show that covalently coupling a …
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