2018年12月20日星期四

Mapping membrane activity in undiscovered peptide sequence space using machine learning

Mapping membrane activity in undiscovered peptide sequence space using machine learning

EY Lee, BM Fulan, GCL Wong… - Proceedings of the …, 2016 - National Acad Sciences
There are some∼ 1,100 known antimicrobial peptides (AMPs), which permeabilize
microbial membranes but have diverse sequences. Here, we develop a support vector
machine (SVM)-based classifier to investigate⍺-helical AMPs and the interrelated nature of …


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